![](\"http:\/\/www.erzurumflas.com\/wp-content\/uploads\/2018\/10\/aspirin-her-derde-deva-mi_6372cfd.jpg\")
Toplumda her derde deva olarak kabul edilen aspirinin bilin\u00e7siz kullan\u0131ld\u0131\u011f\u0131nda hasta veya sa\u011fl\u0131kl\u0131 ki\u015filerde sak\u0131ncal\u0131 durumlara neden olabilece\u011fini s\u00f6yleyen Prof. Dr. Hamza Duygu, y\u00fcksek dozda aspirin kullan\u0131m\u0131n\u0131n, mide kanamas\u0131 riskini artt\u0131rd\u0131\u011f\u0131n\u0131 belirtti.<\/p>\n
Son d\u00f6nemde ger\u00e7ekle\u015ftirilen ara\u015ft\u0131rmalar\u0131n, bilin\u00e7siz kullan\u0131lan aspirinin sak\u0131ncal\u0131 durumlara neden olabilece\u011fini ortaya koydu\u011funu s\u00f6yleyen Yak\u0131n Do\u011fu \u00dcniversitesi Hastanesi Kardiyoloji Anabilim Dal\u0131 Prof. Dr. Hamza Duygu, y\u00fcksek dozda kullan\u0131lan aspirinin, mide kanamas\u0131na neden oldu\u011funu belirtti.<\/p>\n
\u201cY\u00fcksek dozda aspirin kullan\u0131m\u0131 mide kanamas\u0131 riskini art\u0131r\u0131yor\u201d<\/p>\n
Aspirinin a\u011f\u0131z yoluyla al\u0131nd\u0131ktan yar\u0131m saat sonra kana ge\u00e7ti\u011fini ve etkisinin 7-10 g\u00fcn aras\u0131 devam etti\u011fini s\u00f6yleyen Duygu, aspirinin p\u0131ht\u0131 olu\u015fumunda rol oynayan trombosit denilen kan h\u00fccrelerinin birbirine yap\u0131\u015fmas\u0131n\u0131 ve dolay\u0131s\u0131yla da p\u0131ht\u0131 olu\u015fumunu \u00f6nledi\u011fini belirtti. Bu enzimlerin ayn\u0131 zamanda mide \u00fcst duvar\u0131nda koruyucu olarak bulundu\u011funu ve aspirin kullan\u0131m\u0131 nedeniyle azald\u0131\u011f\u0131 i\u00e7in, mide ve ba\u011f\u0131rsak kanamalar\u0131nda art\u0131\u015fa neden oldu\u011funu kaydeden Duygu, \u00f6zellikle y\u00fcksek dozda aspirin kullan\u0131m\u0131n\u0131n kanama riskini artt\u0131rd\u0131\u011f\u0131n\u0131, bu nedenle aspirinle birlikte mide koruyucu ila\u00e7lar\u0131n tavsiye edildi\u011fini s\u00f6yledi.<\/p>\n
Kimler aspirinden uzak durmal\u0131?<\/p>\n
75-30 mg\u2019l\u0131k aspirin kullan\u0131m\u0131n\u0131n kalp krizi ge\u00e7iren, kalp-beyin-bacak ya da \u015fah damarlar\u0131nda t\u0131kan\u0131kl\u0131k saptanan, balon, stent, by-pass uygulanan, inme ge\u00e7iren hastalara tavsiye edildi\u011fini ifade eden Duygu, her g\u00fcn d\u00fczenli aspirin kullanan bu ki\u015filerde 10 y\u0131l i\u00e7inde, kalp krizi ve beyin damar t\u0131kan\u0131kl\u0131\u011f\u0131 riskinin y\u00fczde 20\u2019nin \u00fczerinde bir azalma sa\u011flad\u0131\u011f\u0131n\u0131 s\u00f6yledi. Daha \u00f6nce kalp krizi ge\u00e7irmemi\u015f hastalara koruyucu ama\u00e7l\u0131 aspirin verilmesinin ise hala tart\u0131\u015f\u0131lan bir konu oldu\u011funu kaydeden Duygu, yap\u0131lan yak\u0131n zamanl\u0131 b\u00fcy\u00fck \u00e7al\u0131\u015fmalar\u0131n, g\u00fcnl\u00fck 100 mg aspirin kullan\u0131m\u0131n\u0131n kalp krizi riskini hafif azaltmakla birlikte kanama riskini art\u0131rd\u0131\u011f\u0131n\u0131, bu nedenle, daha \u00f6nce kalp krizi ge\u00e7irmemi\u015f hastalara aspirin tedavisi ba\u015flan\u0131rken, yararlar\u0131 ve zararlar\u0131n\u0131n g\u00f6z \u00f6n\u00fcne al\u0131narak karar verilmesi gerekti\u011finin alt\u0131n\u0131 \u00e7izdi.<\/p>\n
\u201cHangi hastalara aspirin verilmesi gerekti\u011fi, hangi hastalarda ka\u00e7\u0131n\u0131lmas\u0131 gerekti\u011fi konusu, hastan\u0131n ayr\u0131nt\u0131l\u0131 de\u011ferlendirilmesi ve sigara, \u015feker hastal\u0131\u011f\u0131, ya\u015f, hipertansiyon, kolesterol y\u00fcksekli\u011fi, ailede gen\u00e7 ya\u015fta kriz ge\u00e7irme \u00f6yk\u00fcs\u00fc gibi risk fakt\u00f6rleri ile e\u015flik eden hastal\u0131klar ve hastan\u0131n kanama riski g\u00f6z \u00f6n\u00fcne al\u0131narak de\u011ferlendirilmelidir\u201d diyen Duygu, kalp damar hastal\u0131\u011f\u0131na dair olay ya\u015famam\u0131\u015f ki\u015filerde koruyucu ama\u00e7l\u0131 aspirin kullan\u0131m\u0131na kanama riski ve beklenen yarar g\u00f6z \u00f6n\u00fcne al\u0131narak ba\u015flanmas\u0131 en \u00f6nemlisi de hekime dan\u0131\u015f\u0131lmaks\u0131z\u0131n rutin rastgele aspirin al\u0131nmas\u0131n\u0131n yarardan \u00e7ok zarar getirebilece\u011finin unutulmamas\u0131 gerekti\u011fini ifade etti.