{"id":155445,"date":"2015-11-23T09:24:21","date_gmt":"2015-11-23T07:24:21","guid":{"rendered":"http:\/\/www.erzurumflas.com\/kanser-arastirmalarinda-rota-kok-hucreye-cevrildi\/"},"modified":"2015-11-23T09:24:25","modified_gmt":"2015-11-23T07:24:25","slug":"kanser-arastirmalarinda-rota-kok-hucreye-cevrildi","status":"publish","type":"post","link":"https:\/\/www.erzhaber.com\/?p=155445","title":{"rendered":"Kanser Ara\u015ft\u0131rmalar\u0131nda Rota K\u00f6k H\u00fccreye \u00c7evrildi"},"content":{"rendered":"

\u0130STANBUL (\u0130HA) \u2013 Maltepe \u00dcniversitesi Kanser ve K\u00f6k H\u00fccre Ara\u015ft\u0131rma Merkezi, kanser ara\u015ft\u0131rmalar\u0131nda rotay\u0131 k\u00f6k h\u00fccreye \u00e7evirdi. Merkez M\u00fcd\u00fcr\u00fc Prof. Dr. Ranan G\u00fclhan Akta\u015f\u2019a g\u00f6re; kanserin tedaviye diren\u00e7 g\u00f6stermesine ve de yay\u0131lmas\u0131na neden olan kanser k\u00f6k h\u00fccreleri ile yap\u0131lacak sava\u015f\u0131n kazan\u0131labilmesi tedaviside \u00e7ok \u00f6nemli bir ad\u0131m\u0131n at\u0131lmas\u0131n\u0131 sa\u011flayacak.<\/p>\n

Kanser ara\u015ft\u0131rmalar\u0131, t\u0131ptaki geli\u015fmelere paralel olarak her ge\u00e7en g\u00fcn ilerleme kaydediyor. Hastalar\u0131n umutlar\u0131n\u0131 artt\u0131ran bu geli\u015fmelere ra\u011fmen neredeyse her hafta medyada yer alan \u2018Kansere \u00e7are bulundu\u2019 ve \u2018\u0130\u015fte kanserin \u00e7\u00f6z\u00fcm\u00fc\u2019 gibi haberler hayal k\u0131r\u0131kl\u0131klar\u0131na neden olabiliyor. Kansere ili\u015fkin y\u00fczeysel ve \u2018kesin(!)\u2019 \u00e7\u00f6z\u00fcm \u00f6nerileri sunmak yerine, hastal\u0131\u011f\u0131n ortaya \u00e7\u0131kmas\u0131na ve yay\u0131lmas\u0131na neden olan k\u00f6k h\u00fccrelerini bilimsel olarak incelemek amac\u0131yla 1 y\u0131l \u00f6nce kurulan Maltepe \u00dcniversitesi Kanser ve K\u00f6k H\u00fccre Ara\u015ft\u0131rma Merkezi, kanserin tamamen v\u00fccudun d\u0131\u015f\u0131na at\u0131lmas\u0131 ve tekrarlamamas\u0131 i\u00e7in \u00e7al\u0131\u015f\u0131yor.<\/p>\n

KANSER K\u00d6K H\u00dcCRES\u0130<\/p>\n

Son y\u0131llarda kanserle ilgili \u00e7ok say\u0131da \u00e7al\u0131\u015fma yap\u0131lmas\u0131na ra\u011fmen halen baz\u0131 kanser t\u00fcrlerinde istenilen tedavi \u015fekline ula\u015f\u0131lamad\u0131\u011f\u0131n\u0131 belirten Maltepe \u00dcniversitesi Kanser ve K\u00f6k H\u00fccre Ara\u015ft\u0131rma Merkezi M\u00fcd\u00fcr\u00fc Prof. Dr. Ranan G\u00fclhan Akta\u015f, \u201c\u00c7ok say\u0131da kanser hastas\u0131 tedavi edildi zannediliyor fakat bir s\u00fcre sonra hastal\u0131k kendisini tekrarl\u0131yor. Bunun sebebinin kanserli dokuda k\u00f6k h\u00fccre \u00f6zelliklerine benzeyen h\u00fccreler oldu\u011fu tespit edildi. Kanser k\u00f6k h\u00fccresi ad\u0131 verilen bu h\u00fccrelerin kanserin tamamen tedavi edilememesinin ve n\u00fcksetmesinin sebebi olabilece\u011fi konusunda \u00e7ok \u00f6nemli \u00e7al\u0131\u015fmalar ortaya \u00e7\u0131kar\u0131ld\u0131. Biz de bu h\u00fccrelere ula\u015fman\u0131n ve onlar\u0131 kanserli dokudan temizlemenin yollar\u0131n\u0131 ara\u015ft\u0131r\u0131yoruz\u201d dedi.<\/p>\n

4 KR\u0130T\u0130K ADIM<\/p>\n

K\u00f6k h\u00fccrelerin farkl\u0131la\u015fma, kendilerini yenileme ve \u00e7o\u011falma \u00f6zellikleri ta\u015f\u0131d\u0131\u011f\u0131n\u0131 belirten Akta\u015f, \u201cV\u00fccudumuzda yer alan ve hem farkl\u0131la\u015fma hem de yenilenebilme \u00f6zellikleri olan k\u00f6k h\u00fccrelerin, kanserli dokularda da var oldu\u011fu g\u00f6r\u00fcld\u00fc. Yani kanserli dokular i\u00e7erisinde bir grup h\u00fccre kendisini yenileyebiliyor, farkl\u0131la\u015fabiliyor, sessiz kalabiliyor ve de uygun ortam buldu\u011funda \u00e7o\u011falarak kanserin yeniden o b\u00f6lgede yay\u0131lmas\u0131na sebep olabiliyor. Hatta farkl\u0131 kanser t\u00fcrlerinin tedavi edilememesinin bir sebebinin de tedaviye diren\u00e7li olan bu h\u00fccreler oldu\u011fu \u00fczerinde duruluyor. \u00d6yle ki kanser k\u00f6k h\u00fccrelerinin dokuda ne d\u00fczeyde oldu\u011funun saptanmas\u0131, kanserin seyri a\u00e7\u0131s\u0131ndan da \u00f6nem ta\u015f\u0131yor\u201d dedi.<\/p>\n

Kanser tedavisinde k\u00f6k h\u00fccre ara\u015ft\u0131rmalar\u0131n\u0131n \u00f6nemini vurgulayan Ranan G\u00fclhan Akta\u015f, bu h\u00fccrelerle m\u00fccadeledeki 4 kritik ad\u0131m\u0131 \u015f\u00f6yle s\u0131ralad\u0131: \u201c\u0130lk olarak kanser k\u00f6k h\u00fccrelerine ula\u015fmal\u0131y\u0131z. Ard\u0131ndan doku i\u00e7erisinde onlar\u0131 tan\u0131mal\u0131y\u0131z. Daha sonra yine doku i\u00e7erisinde bu h\u00fccreleri \u00f6ld\u00fcrmeliyiz. Son olarak da kanserli dokunun yay\u0131lmas\u0131na engel olmal\u0131y\u0131z.\u201d<\/p>\n

\u201cKARAC\u0130\u011eER KANSER\u0130 \u00dcZER\u0130NE OLAN \u00c7ALI\u015eMALARIMIZDA YO\u011eUNLA\u015eTIK\u201d<\/p>\n

Karaci\u011fer kanseri \u00fczerine \u00e7al\u0131\u015fmalarda yo\u011funla\u015ft\u0131klar\u0131n\u0131 belirten Akta\u015f, \u201cKaraci\u011fer kanserli h\u00fccreler i\u00e7erisinde bu t\u00fcr h\u00fccreler saptad\u0131k. \u015eimdi bu h\u00fccrelerin davran\u0131\u015f\u0131n\u0131 izliyoruz ve farkl\u0131 k\u00fclt\u00fcr ortamlar\u0131nda nas\u0131l \u00e7o\u011fald\u0131klar\u0131na bak\u0131yoruz. Bunlar hen\u00fcz laboratuvarda yap\u0131lan \u00e7al\u0131\u015fmalar. Bu \u00e7al\u0131\u015fmalar bir miktar daha ilerleyince t\u0131ptaki t\u00fcm \u00e7al\u0131\u015fmalar gibi \u00f6nce hayvan deneyleri yapaca\u011f\u0131z ve ard\u0131ndan da klinik uygulamalara ge\u00e7ece\u011fiz\u201d diye konu\u015ftu.<\/p>\n

\u0130LK YILDA 5 \u00d6D\u00dcL<\/p>\n

Maltepe \u00dcniversitesi Kanser ve K\u00f6k H\u00fccre Ara\u015ft\u0131rma Merkezi, kurulu\u015funun ilk y\u0131l\u0131n\u0131 5 \u00f6d\u00fclle tamamlad\u0131. Merkez, The American Society for Cell Biology and International Federation of Cell Biology Meeting\u2019de International Travel Award, 14. Ulusal T\u0131bbi Biyoloji ve Genetik Kongresi\u2019nde Gen\u00e7 Ara\u015ft\u0131rmac\u0131, 14. Ulusal T\u0131bbi Biyoloji ve Genetik Kongresi\u2019nde En \u0130yi S\u00f6zl\u00fc Sunum, T\u0131p Fak\u00fcltesi \u00d6\u011frencileri Kongresi\u2019nde En \u0130yi Poster Sunum kategorisinde 1.\u2019lik ve T\u0131p Fak\u00fcltesi \u00d6\u011frencileri Kongresi\u2019nde En \u0130yi Poster Sunum kategorisinde 3.\u2019l\u00fck \u00f6d\u00fcllerini kazand\u0131.